Author: dweetleapp

  • FDA names Dr Richard Pazdur to replace George Tidmarsh as CDER Director

    The FDA-veteran and oncology specialist will lead the US drug agency’s work ensuring the safety and efficacy of medicines. The US Food and Drug Administration (FDA)’s Center for Drug Evaluation and Research (CDER) has appointed 26-year agency veteran Dr Richard Pazdur as its new director. The internal hire will see Dr Pazdur remain in his read more

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    FDA names Dr Richard Pazdur to replace George Tidmarsh as CDER Director

  • Pharma's sustainability push continues as Merck signs renewable energy deal

    The German pharma company’s agreement for its South Korea sites is the latest green initiative to be unveiled by the industry. Merck has become one of the latest pharma companies to signal its commitment to manufacturing sustainability, signing a renewable energy agreement for its business in South Korea (pictured above). Its deal with local green read more

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    Pharma's sustainability push continues as Merck signs renewable energy deal

  • Roche’s fenebrutinib shows best-in-disease potential in MS

    Phase III data suggest the drug could be the first high-efficacy, oral therapy for relapsing multiple sclerosis (RMS) or primary progressive multiple sclerosis. Roche’s oral multiple sclerosis fenebrutinib is continuing on its path to become the first Bruton’s tyrosine kinase (BTK) inhibitor for both the relapsing and primary progressive forms of the condition. In the read more

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    Roche’s fenebrutinib shows best-in-disease potential in MS

  • GM iPSCs see clinical-scale platelet manufacturing potential

    By utilising patient-derived instead of donor-derived platelets, the method could offer a safer approach to platelet transfusions. A novel method for manufacturing platelet-producing cells from stem cells, known as megakaryocytes, could provide an unlimited supply of patient-derived platelets. Notably, the proposed approach outlined by researchers in Japan also avoids the risk of immune rejection, making read more

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    GM iPSCs see clinical-scale platelet manufacturing potential

  • MHRA approves Leqembi IV as additional Alzheimer’s option

    Decision provides UK Alzheimer’s patients with an alternative administration method for Eisai and Biogen’s antibody drug. Credit: PictureDesignSwiss / Shutterstock.com Eisai and Biogen have received UK approval for intravenous (IV) maintenance dosing of Leqembi (lecanemab) for patients with early Alzheimer’s, expanding treatment options for the disease. The Medicines and Healthcare products Regulatory Agency (MHRA)’s authorisation read more

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    MHRA approves Leqembi IV as additional Alzheimer’s option

  • Surgical device increases range of motion in hip arthroscopy

    A close look at the fully equipped CAP-LIFT cannula. Image source: University of Colorado Boulder/Jacob Segil Hip arthroscopy, a type of minimally invasive joint surgery, has become increasingly popular as of late. According to a study in the Iowa Orthopaedic Journal, the procedure has seen a 600% increase in utilization over the past 15 years read more

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    Surgical device increases range of motion in hip arthroscopy

  • Why women are three times more likely to get severe long Covid

    The team also found lower red blood cell production or anemia in the female patients. This suggests that elevated levels of inflammatory factors in females with long Covid adversely affect their blood production, Elahi says. In addition, the researchers uncovered dysregulated sex hormones in the long Covid patients, finding reduced testosterone levels in affected women read more

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    Why women are three times more likely to get severe long Covid

  • 70+ Artists Transform Matchboxes for Joy Machine's 'General Strike'

    Joy Machine is excited to present General Strike, an exhibition of 70+ matchboxes, opening on November 21 in Chicago. What does solidarity mean for the artist? Or, what can art do in a time of crisis? The concept of a general strike is appealing to many advocates and activists because, in the face of oppression read more

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    70+ Artists Transform Matchboxes for Joy Machine's 'General Strike'

  • Digital Nomad Guide to Living in Scandinavia – Goats On The Road

    You close your laptop, throw on your backpack and step outside. The air’s cool and smells like pine with just a hint of snow. Somewhere out across the fjord, you can hear birds singing. That postcard-perfect scene? It’s not a dream… It’s Scandinavia. If you’re a digital nomad, you’re always chasing that sweet spot – read more

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    Digital Nomad Guide to Living in Scandinavia – Goats On The Road

  • 16 Statistical Process Control in Python | System Reliability and Six Sigma in R and Python

    Figure 2.1: Statistical Process Control! In this workshop, we will learn how to perform statistical process control in Python, using statistical tools and plotnine visualizations! Statistical Process Control refers to using statistics to (1) measure variation in product quality over time and (2) identify benchmarks to know when intervention is needed. Let’s get started! Getting read more

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    16 Statistical Process Control in Python | System Reliability and Six Sigma in R and Python

  • AI spots hidden objects lodged in patients' airways on CT

    3D reconstruction of the airways generated from a CT scan using AI Image source: University of Southampton To address this challenge, the research team created a deep learning model. It combines a high-precision airway mapping technique (MedpSeg) with a neural network that analyses CT images for hidden signs of foreign bodies. The model was trained read more

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    AI spots hidden objects lodged in patients' airways on CT

  • AI and apps not enough to solve mental health crisis, experts warn

    The advisory emphasizes that while technology has immense potential to help psychologists address the mental health crisis it must not distract from the urgent need to fix the foundations of America’s mental health care system. The report offers recommendations for the public, policymakers, tech companies, researchers, clinicians, parents, caregivers and other stakeholders to help them read more

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    AI and apps not enough to solve mental health crisis, experts warn

  • Tetsunori Tawaraya’s Fierce & Hypnotizing World Will Air-Fry Your Retinas – Hi-Fructose Magazine

    Speculative genres like sci-fi are so cross-pollinated with horror and fantasy and the Western that the conventions of one frequently bleed into the others. “Ghetto Samurai” brings the genre-blending eastward, and nods to the cowboy motifs that became integral to conventions of post-war samurai films in Japan. “Story does not flow out at all,” Tawaraya read more

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    Tetsunori Tawaraya’s Fierce & Hypnotizing World Will Air-Fry Your Retinas – Hi-Fructose Magazine

  • Stress cardiac MRI tests may help improve angina diagnosis and treatment

    Clinical practice should now change to include a stress cardiac MRI test for angina, especially for women with chest pain and no blockages in the main arteries Colin Berry After following all participants for at least 12 months, the analysis found: About half of all participants (53%) had a diagnosis change after the stress cardiac read more

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    Stress cardiac MRI tests may help improve angina diagnosis and treatment

  • New approach for targeted seizure control without surgery

    Jerzy Szablowski Image source: Rice University; photo by Jeff Fitlow “Many neurological diseases are driven by hyperactive cells at a particular location in the brain,” said study lead Jerzy Szablowski, assistant professor of bioengineering and a member of the Rice Neuroengineering Initiative. “Our approach aims the therapy where it is needed and lets you control read more

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    New approach for targeted seizure control without surgery

  • Smart HealthTech Built on Digital Trust

    Precision That Keeps Healthcare Moving Underpinning these healthcare solutions is a foundation of precision engineering. At the heart of every great medical device is a component manufactured with absolute precision. CNC Star specializes in high-precision components for endoscopy: small to medium batches, rapid prototypes, and urgent orders supported by capabilities in reverse engineering and fine-tolerance read more

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    Smart HealthTech Built on Digital Trust

  • Phantom Limbs: The Body Part Filled Paintings of Sarah Slappey are Tumultuous, Alluring, & Aggressive – Hi-Fructose Magazine

    Beyond her distinctive imagery and thematic explorations, Slappey’s technical skills are also exceptional, lending an almost photorealistic quality to elements of her work. Her paintings have both a recognizable look as well as a unique feel. She produces the kind of imagery that is not just visually captivating but also stirring, the kind that elicits read more

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    Phantom Limbs: The Body Part Filled Paintings of Sarah Slappey are Tumultuous, Alluring, & Aggressive – Hi-Fructose Magazine

  • Ultrasound update for organ imaging

    AI opens new possibilities When it comes to deeper anatomical structures, ultrasound quickly reaches its limits, and the physical limitations of air-filled structures remain unchanged, Dr Trenker pointed out. The high level of examiner dependency also continues to be an issue – but this could change in the future: New publications suggest, for example, that read more

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    Ultrasound update for organ imaging

  • Thyroid gland: unexpected key to prostate cancer treatment

    Jenny Persson, Professor, Department of Molecular Biology, Umeå University, Sweden Image source: Umeå University; photo: Mattias Petterson Blocking TRβ using NH-3 worked by leading to the elimination of a particular signal, the androgen receptor signal, which is otherwise activated by testosterone and then plays a central role in the development of prostate cancer. A review read more

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    Thyroid gland: unexpected key to prostate cancer treatment

  • Personal Effects: The Art of Laurie Lipton – Hi-Fructose Magazine

    The drawings of Laurie Lipton have bewildered and enchanted audiences for several decades. Each piece wields a cacophony of influences and experiences in dreamlike visions. When she talks about her work, whether from the 1980s or recent months, Lipton yields any specific explanation to the viewer. “Everything I’ve ever seen, read, felt, thought, heard… it read more

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    Personal Effects: The Art of Laurie Lipton – Hi-Fructose Magazine